Abstract
The bachelor's thesis “Optimization of a Sample Preparation Strategy for the Preconcentration and Matrix Separation of Lead in Seawater for Subsequent Characterization using ICP-MS, ICP-MS/MS, and MC ICP-MS” focuses on developing and optimizing methods for analyzing lead isotopes in seawater. This research is particularly relevant because lead is a toxic heavy metal, and its low concentrations and complex matrix in seawater pose significant challenges to lead analysis.
The study addresses a knowledge gap by developing an innovative sample preparation strategy that enhances lead preconcentration and matrix separation. The primary goal was to minimize analytical interferences and improve the precision of lead isotope ratios.
The methodology involved three different types of mass spectrometry: ICP-MS, ICP-MS/MS, and MC ICP-MS. These were complemented by various sample preparation techniques, including the use of the seaFAST system, freeze-drying, and filtration with the EmporeTM SPE extraction disks. The combined approach enabled effective sample preparation and significantly improved analytical results.
The results demonstrated that the developed method provides reliable measurements of lead isotope ratios while significantly reducing interferences, particularly from 204Hg. Real samples collected from the North Sea with the ATAIR expedition (voyage number: 067I033-1) validated the method's applicability.
In conclusion, the thesis establishes a robust foundation for future studies on environmental monitoring and source attribution of lead in marine systems. Future research could focus on adapting this method for other heavy metals and isotope systems to further expand its analytical capabilities.
DOI Link to Publication