Enzymatic Monolayer Degradation Study of Multiblock Copolymers consisting of Poly(epsilon-caprolactone) and Poly(p-dioxanone) Blocks

Reiche, J.; Kulkarni, A.; Kratz, K.; Lendlein, A.

Journalpaper

Enzymatic Monolayer Degradation Study of Multiblock Copolymers consisting of Poly(epsilon-caprolactone) and Poly(p-dioxanone) Blocks

Abstract

Multiblock copolymers consisting of poly-ε-caprolactone- (PCL) segments and poly-p-dioxanone- (PPDO) segments were analysed with respect to their hydrolytic degradation behaviour using the Langmuir monolayer degradation technique. Degradation was studied both on phosphate buffer subphase and on aqueous subphases containing phosphate buffered pseudomonas lipase. The influence of systematic structure variation of the block copolymers on the monolayer degradation kinetics is studied. A model explaining the unexpected linear degradation behaviour of the monolayers is developed.

DOI Link to Publication

URL: https://publications.hereon.de/id/26079/
Authors:Reiche, J., Kulkarni, A., Kratz, K., Lendlein, A.
Year:2008
In: Thin Solid Films
Volume:516
Issue:24
Pages:8821 - 8828
Publisher:Elsevier
Type:Journalpaper
ISSN: 0040-6090
Cite as: Reiche, J.; Kulkarni, A.; Kratz, K.; Lendlein, A.: Enzymatic Monolayer Degradation Study of Multiblock Copolymers consisting of Poly(epsilon-caprolactone) and Poly(p-dioxanone) Blocks. In: Thin Solid Films. Vol. 516 (2008) 24, 8821 - 8828. (DOI: 10.1016/j.tsf.2007.11.053)