@misc{moreno_ciprofloxacin_release_2023, 
author={Moreno, L., Wang, C., Lamaka, S.V., Zheludkevich, M.L., Rodríguez-Hernández, J., Arrabal, R., Matykina, E.},
title={Ciprofloxacin Release and Corrosion Behaviour of a Hybrid PEO/PCL Coating on Mg3Zn0.4Ca Alloy},
year={2023},
howpublished = {journal article},
doi = {https://doi.org/10.3390/jfb14020065},
abstract = {In the present work, a hybrid hierarchical coating (HHC) system comprising a plasma electrolytic oxidation (PEO) coating and a homogeneously porous structured polycaprolactone (PCL) top-coat layer, loaded with ciprofloxacin (CIP), was developed on Mg3Zn0.4Ca alloy. According to the findings, the HHC system avoided burst release and ensured gradual drug elution (64% over 240 h). The multi-level protection of the magnesium alloy is achieved through sealing of the PEO coating pores by the polymer layer and the inhibiting effect of CIP (up to 74%). The corrosion inhibition effect of HHC and the eluted drug is associated with the formation of insoluble CIP-Me (Mg/Ca) chelates that repair the defects in the HHC and impede the access of corrosive species as corroborated by FTIR spectra, EIS and SEM images after 24 h of immersion. Therefore, CIP participates in an active protection mechanism by interacting with cations coming through the damaged coating.},
note = {Online available at: \url{https://doi.org/10.3390/jfb14020065} (DOI). Moreno, L.; Wang, C.; Lamaka, S.; Zheludkevich, M.; Rodríguez-Hernández, J.; Arrabal, R.; Matykina, E.: Ciprofloxacin Release and Corrosion Behaviour of a Hybrid PEO/PCL Coating on Mg3Zn0.4Ca Alloy. Journal of Functional Biomaterials. 2023. vol. 14, no. 2, 65. DOI: 10.3390/jfb14020065}}