%0 journal article %@ 0142-9612 %A Drzeniek, N.M., Kahwaji, N., Schlickeiser, S., Reinke, P., Geißler, S., Volk, H.-D., Gossen, M. %D 2023 %J Biomaterials %P 121971 %R doi:10.1016/j.biomaterials.2022.121971 %T Immuno-engineered mRNA combined with cell adhesive niche for synergistic modulation of the MSC secretome %U https://doi.org/10.1016/j.biomaterials.2022.121971 %X Integrating minimally immunogenic mRNA technology with predesigned matrix-derived cues allows for the synergistic combination of multiple dimensions of cell manipulation and opens routes for biomaterial-based delivery of mRNA-engineered cell products. Such multimodal systems could present a more biologically relevant way to therapeutically address complex multifactorial processes such as tissue ischemia, angiogenesis, and regeneration.