%0 journal article
%@ 1742-7061
%A Peruzzi, N., Galli, S., Helmholz, H., Kardjilov, N., Krüger, D., Markötter, H., Moosmann, J., Orlov, D., Prgomet, Z., Willumeit-Römer, R., Wennerberg, A., Bech, M.

%D 2021
%J Acta Biomaterialia

%P 582-591 
%R doi:10.1016/j.actbio.2021.09.047
%T Multimodal ex vivo methods reveal that Gd-rich corrosion byproducts remain at the implant site of biodegradable Mg-Gd screws
%U https://doi.org/10.1016/j.actbio.2021.09.047
 
%X Gadolinium is among the most promising alloying elements for property control in biodegradable magnesium alloy implants, but its toxicity is controversial and its behavior during corrosion needs to be investigated. We combine 2D energy dispersive x-ray spectroscopy and 3D neutron and x-ray tomography to image the degradation of magnesium-gadolinium implants after 12 weeks of healing time. We find that, at the time in exam, the corrosion has involved only the magnesium component, while the gadolinium remains localized at the implant site. X-ray fluorescence analysis of the main excretory organs also does not reveal any measurable accumulation of Gd, further reinforcing the conclusion that very limited or no removal at all of Gd-alloy has happened during degradation.