%0 journal article
%@ 1386-0291
%A Reinthaler, M., Baeckemo-Johansson, J., Braune, S., Al-Hindwan, H.S.A., Lendlein, A., Jung, F.

%D 2019
%J Clinical Hemorheology and Microcirculation
%N 2
%P 183-191 
%R doi:10.3233/CH-189410
%T Shear-induced platelet adherence and activation in an in-vitro dynamic multiwell-plate system
%U https://doi.org/10.3233/CH-189410
2 
%X Differences in the thrombogenicity of the studied polymers were more pronounced when tested at high agitation speed due to the induced shear stresses. Testing under varying shear stresses, thus, led to a different evaluation of the implant thrombogenicity, which emphasizes the need for testing under various flow conditions. Our data further confirmed earlier findings where the same reference implants were tested under static (and not dynamic) conditions and with fresh human platelet rich plasma instead of whole blood. This supports that the application of common reference materials may improve inter-study comparisons, even under varying test conditions.