%0 journal article %@ 0002-8703 %A Reinthaler, M., Ozga, A.-K., Sinning, D., Curio, J., Al-Hindwan, H.S., Baeckemo-Johansson, J., Jung, F., Lendlein, A., Rauch, G., Landmesser, U. %D 2018 %J American Heart Journal %P 95-102 %R doi:10.1016/j.ahj.2018.03.025 %T Revival of transcatheter PFO closure: A meta-analysis of randomized controlled trials - impact of shunt size and age %U https://doi.org/10.1016/j.ahj.2018.03.025 %X According to our meta-analysis TPC plus antiplatelets was superior in terms of stroke prevention when compared to Med-Tx. Furthermore, patients with moderate to severe shunts and those younger than 45 years of age were found to benefit most from TPC.