@misc{hehn_propagationbased_phasecontrast_2018, author={Hehn, L., Gradl, R., Voss, A., Guenther, B., Dierolf, M., Jud, C., Willer, K., Allner, S., Hammel, J.U., Hessler, R., Morgan, K.S., Herzen, J., Hemmert, W., Pfeiffer, F.}, title={Propagation-based phase-contrast tomography of a guinea pig inner ear with cochlear implant using a model-based iterative reconstruction algorithm}, year={2018}, howpublished = {journal article}, doi = {https://doi.org/10.1364/BOE.9.005330}, abstract = {Propagation-based phase-contrast computed tomography has become a valuable tool for visualization of three-dimensional biological samples, due to its high contrast between materials with similar attenuation properties. However, one of the most-widely used phase-retrieval algorithms imposes a homogeneity assumption onto the sample, which leads to artifacts for numerous applications where this assumption is violated. Prominent examples are biological samples with highly-absorbing implants. Using synchrotron radiation, we demonstrate by the example of a guinea pig inner ear with a cochlear implant electrode, how a recently developed model-based iterative algorithm for propagation-based phase-contrast computed tomography yields distinct benefits for such a task. We find that the model-based approach improves the overall image quality, removes the detrimental influence of the implant and accurately visualizes the cochlea.}, note = {Online available at: \url{https://doi.org/10.1364/BOE.9.005330} (DOI). Hehn, L.; Gradl, R.; Voss, A.; Guenther, B.; Dierolf, M.; Jud, C.; Willer, K.; Allner, S.; Hammel, J.; Hessler, R.; Morgan, K.; Herzen, J.; Hemmert, W.; Pfeiffer, F.: Propagation-based phase-contrast tomography of a guinea pig inner ear with cochlear implant using a model-based iterative reconstruction algorithm. Biomedical Optics Express. 2018. vol. 9, no. 11, 5330-5339. DOI: 10.1364/BOE.9.005330}}