%0 journal article %@ 0937-941X %A Wu, L., Luthringer, B.J.C., Feyerabend, F., Zhang, Z., Machens, H.G., Maeda, M., Taipaleenmaeki, H., Hesse, E., Willumeit-Roemer, R., Schilling, A.F. %D 2017 %J Osteoporosis International %N 11 %P 3215-3228 %R doi:10.1007/s00198-017-4163-4 %T Increased levels of sodium chloride directly increase osteoclastic differentiation and resorption in mice and men %U https://doi.org/10.1007/s00198-017-4163-4 11 %X The reported that enhanced bone resorption after high-sodium diets may not only be secondary to the urinary calcium loss but may also be a direct, cell-mediated effect on osteoclastic resorption. These findings allow us to suggest an explanation for the clinical findings independent of a PTH-mediated regulation.