@misc{kaessmeyer_organotypic_softtissue_2016, author={Kaessmeyer, S., Sehl, J., Khiao In, M., Hiebl, B., Merle, R., Jung, F., Franke, R.P., Plendl, J.}, title={Organotypic soft-tissue co-cultures: Morphological changes in microvascular endothelial tubes after incubation with iodinated contrast media}, year={2016}, howpublished = {journal article}, doi = {https://doi.org/10.3233/CH-168119}, abstract = {RESULTS: In the organotypic soft-tissue co-cultures with fibroblasts, the endothelial cells developed three-dimensional capillary-like structures which expanded via sprouting branches. After incubation with the different CM, the numbers of endothelial tubes (p = 0.001) and their lengths (p = 0.003) were significantly lower after the 5 minutes incubation time, when compared to the 1.5 minutes incubation time. The tubular diameters were significantly reduced after 5 minutes (p < 0.001), when compared to the 1.5 minutes incubation duration. Interestingly, Iomeprol and Iodixanol induced an elongation of the tubular branches during incubation duration of 1.5 minutes (p = 0.015). However, after 5 minutes incubation, the tubular branches were drastically shorter in the presence of Iomeprol and Iodixanol than the tubular branches of the control (p = 0.007).}, note = {Online available at: \url{https://doi.org/10.3233/CH-168119} (DOI). Kaessmeyer, S.; Sehl, J.; Khiao In, M.; Hiebl, B.; Merle, R.; Jung, F.; Franke, R.; Plendl, J.: Organotypic soft-tissue co-cultures: Morphological changes in microvascular endothelial tubes after incubation with iodinated contrast media. Clinical Hemorheology and Microcirculation. 2016. vol. 64, no. 3, 391-402. DOI: 10.3233/CH-168119}}