@article{yang_biodegradable_carriergene_2015, author={Yang, J. and Feng, Y. and Zhang, L.}, title={Biodegradable carrier/gene complexes to mediate the transfection and proliferation of human vascular endothelial cells}, year={2015}, journal = {Polymers for Advanced Technologies}, volume = {26}, number = {12}, pages = {1370 - 1377}, doi = {http://dx.doi.org/10.1002/pat.3636}, abstract = {Artificial vascular scaffolds have been developed and used clinically for many years, but the lack of a living functional layer of human umbilical vein endothelial cells (HUVECs) remains a significant challenge, especially for small diameter artificial blood vessels. Endothelialization of artificial vascular scaffolds has been proved as one of the most potential approaches to improve their hemocompatibility and long-term patency. A variety of non-viral gene carriers have been investigated to mediate the transfection and proliferation of HUVECs. In this mini-review, we will summarize the recent development of the non-viral gene carriers for transfecting HUVECs. The gene transfection with targeting ligand immobilized carriers is a promising approach to enhance endothelialization of artificial vascular scaffolds.}, note = {Online available at: \url{http://dx.doi.org/10.1002/pat.3636} (DOI). Yang, J.; Feng, Y.; Zhang, L.: Biodegradable carrier/gene complexes to mediate the transfection and proliferation of human vascular endothelial cells. In: Polymers for Advanced Technologies. Vol. 26 (2015) 12, 1370 - 1377. (DOI: 10.1002/pat.3636)}}