@misc{golub_xray_and_2013, author={Golub, M., Lott, D., Watkins, E.B., Haramus, V.M., Luthringer, B., Stoermer, M., Schreyer, A., Willumeit, R.}, title={X-ray and neutron investigation of self-assembled lipid layers on a titanium surface}, year={2013}, howpublished = {journal article}, doi = {https://doi.org/10.1186/1559-4106-8-21}, abstract = {Titanium is the most widely preferred metal material for bone reconstruction in orthopedics and dentistry. To improve its biological performance, various coatings can be applied. In this investigation, a biomimetic coating on a model implant surface was studied in X-ray and neutron reflectivity experiments to probe the quality of this coating, which is only few nanometers thick. Titanium was deposited on polished silicon surfaces using a magnetron sputtering technique. To improve the lipid coating’s stability, a stronger van der Waals interaction was first created between the implant surface and the biomimetic coating by adding a phosphonic acid (n-octadecylphosphonic acid – OPA) monolayer onto the surfaces. Then, three monolayers of POPE (phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-ethanolamine) were transferred using the Langmuir-Blodgett (LB) and Langmuir-Schaefer (LS) techniques. The analysis of X-ray and neutron specular reflectivity data shows that OPA molecules cover the model implant surface completely and that approximately 50% coverage of POPE can be achieved by LB and LS transfer.}, note = {Online available at: \url{https://doi.org/10.1186/1559-4106-8-21} (DOI). Golub, M.; Lott, D.; Watkins, E.; Haramus, V.; Luthringer, B.; Stoermer, M.; Schreyer, A.; Willumeit, R.: X-ray and neutron investigation of self-assembled lipid layers on a titanium surface. Biointerphases. 2013. vol. 8, no. 1, 21. DOI: 10.1186/1559-4106-8-21}}