%0 journal article
%@ 1386-0291
%A Hoepken, S., Fuhrmann, R., Jung, F., Franke, R.P.

%D 2009
%J Clinical Hemorheology and Microcirculation
%N 1-2
%P 157-166 
%R doi:10.3233/CH-2009-1230
%T Shear resistance of human umbilical endothelial cells on different materials covered with or without extracellular matrix: Controlled in-vitro study
%U https://doi.org/10.3233/CH-2009-1230
1-2 
%X With the exemption of polyvinyl chloride all other materials could be coated with ECM at least partially. Under static conditions the best results with respect to complete coverage with ECM and HUVEC were seen on polyester and polyurethane. Under shear load, however, the complete HUVEC layer together with the ECM detached from the polymer surface within a short time. ECM and HUVEC remained no longer than 43 minutes on anyone of the materials tested. The materials as supplied and tested were clearly not appropriate as implants in contact to the flowing blood.