@misc{sabat_biology_of_2010, 
author={Sabat, R., Gruetz, G., Warszawska, K., Kirsch, S., Witte, E., Wolk, K., Geginat, J.},
title={Biology of interleukin-10},
year={2010},
howpublished = {journal article},
doi = {https://doi.org/10.1016/j.cytogfr.2010.09.002},
abstract = {Interleukin (IL)-10 is the most important cytokine with anti-inflammatory properties besides TGF-β and IL-35. It is produced by activated immune cells, in particular monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells. IL-10 acts through a transmembrane receptor complex, which is composed of IL-10R1 and IL-10R2, and regulates the functions of many different immune cells. In monocytes/macrophages, IL-10 diminishes the production of inflammatory mediators and inhibits antigen presentation, although it enhances their uptake of antigens. Additionally, IL-10 plays an important role in the biology of B cells and T cells. The special physiological relevance of this cytokine lies in the prevention and limitation of over-whelming specific and unspecific immune reactions and, in consequence, of tissue damage. At the same time, IL-10 strengthens the “scavenger”-function and contributes to induced tolerance. This review provides an overview about the cellular sources, molecular mechanisms, effects, and biological role of IL-10.},
note = {Online available at: \url{https://doi.org/10.1016/j.cytogfr.2010.09.002} (DOI). Sabat, R.; Gruetz, G.; Warszawska, K.; Kirsch, S.; Witte, E.; Wolk, K.; Geginat, J.: Biology of interleukin-10. Cytokine & Growth Factor Reviews. 2010. vol. 21, no. 5, 331-344. DOI: 10.1016/j.cytogfr.2010.09.002}}