%0 journal article
%@ 1662-0356
%A Hofmann, D., Entrialgo, M., Reiche, J., Kratz, K., Lendlein, A.

%D 2010
%J Advances in Science and Technology, 5th Forum on new Materials Part E

%P 16-24 
%R doi:10.4028/www.scientific.net/AST.76.16
%T Molecular Modeling and experimental investigation of hydrolytically degradable polymeric biomaterials
%U https://doi.org/10.4028/www.scientific.net/AST.76.16
 
%X (PLGA)] and copoly(ether)esteruretanes as multiblock copolymers. The molecular modeling approach permits to efficiently investigate the influence of micro-structural properties like free volume distribution, cohesive energy density and concentration of polar functional groups on the bulk water uptake as one constituent part of hydrolytic degradation. The Langmuir monolayer investigations on polymer degradation on the other hand yield the dynamics of bond splitting during degradation within hours separately from time consuming diffusion processes, which may take months in bulk samples.