@misc{mrowietz_reversibility_of_2008, author={Mrowietz, C., Hiebl, B., Franke, R.P., Park, J.-W., Jung, F.}, title={Reversibility of echinocyte formation after contact of erythrocytes with various radiographic contrast media}, year={2008}, howpublished = {journal article}, doi = {https://doi.org/10.3233/CH-2008-1097}, abstract = {These RCM induced echinocyte formation (after suspension of erythrocytes in plasma/RCM mixtures for 10 min at 37°C), which was reversible after resuspension in autologous RCM-free plasma (resuspension time 5 min at 37°C). Especially for Iomeprol and Iopromide – the RCMs which induced the strongest echinocyte formation – an echinocyte reduction from 94.2% to 44.5% and for Iopromide from 80.6% to 50.4% occurred. The echinocyte formation was influenced by the type of RCM as well as by the RCM concentration. The same was true for the reversibility of echinocyte formation due to resuspension in autologous plasma (type of RCM: p≤0.0001; concentration of RCM: p=0.0847). Iodixanol was associated with the least numbers echinocytes formed (after suspension in the plasma/RCM-mixture as well as after the resuspension in autologous plasma). A 100% reversibility back to discocytes was observed in none of the RCMs after resuspension in autologous RCM-free plasma.}, note = {Online available at: \url{https://doi.org/10.3233/CH-2008-1097} (DOI). Mrowietz, C.; Hiebl, B.; Franke, R.; Park, J.; Jung, F.: Reversibility of echinocyte formation after contact of erythrocytes with various radiographic contrast media. Clinical Hemorheology and Microcirculation. 2008. vol. 39, no. 1-4, 281-286. DOI: 10.3233/CH-2008-1097}}