%0 journal article %@ 0896-8446 %A Niemeyer, B., Jansen, J. %D 2007 %J Journal of Supercritical Fluids %N 3 %P 354-361 %R doi:10.1016/j.supflu.2006.03.015 %T An Innovative Approach for Sorptive Separation of Amphiphilic Biomolecules Applying High Hydrostatic Pressure %U https://doi.org/10.1016/j.supflu.2006.03.015 3 %X To realize this approach, interdisciplinary researches were necessary. The surfaces of different silica gels were chemically modified in order to synthesize adsorbents with the desired properties. Two high pressure devices were designed and built. One is an circulation plant to investigate equilibrium states. It was utilized to record adsorption isotherms under a pressure of up to 300 MPa. The second one is a semi-continuous set-up for a fixed bed reactor. It was hydrodynamically characterized and afterwards used to look into breakthrough curves and separation cycles. The adsorption capacity of the tailor made adsorbents and its pressure dependency was examined via these plants in equilibrium (isotherm) and dynamic (breakthrough) experiments. Therefore, the nonionic surfactant Triton X-100 was applied as a model substance for e.g. glycolipids, which are within the scope of the separation method.