%0 journal article %@ 0142-9612 %A Bernhardt, R., Dolder, J.van den, Bierbaum, S., Beutner, R., Scharnweber, D., Jansen, J., Beckmann, F., Worch, H. %D 2005 %J Biomaterials %N 16 %P 3009-3019 %R doi:10.1016/j.biomaterials.2004.08.030 %T Osteoconductive Modifications of Ti-Implants in a Goat Defect Model: Characterization of Bone Growth with SR µCT and Histology %U https://doi.org/10.1016/j.biomaterials.2004.08.030 16 %X For uncoated titanium, RGD, and especially collagen type I, the response in cavity A, situated in denser bone, was stronger than in cavity B. Collagen type III, on the other hand, appeared to be the more effective coating in areas of lesser bone density as represented by cavity B. These results indicate that matrix molecules (or combinations thereof) are capable of generating the appropriate signals for the specific microenvironment around implants and can thus accelerate the bone formation process and increase the stability of implants.