%0 journal article
%@ 1422-0067
%A Willumeit, R.,Moehring, A.,Feyerabend, F.

%D 2014
%J International Journal of Molecular Sciences
%N 5
%P 7639-7650 
%R doi:10.3390/ijms15057639
%T Optimization of Cell Adhesion on Mg Based Implant Materials by Pre-Incubation under Cell Culture Conditions
%U https://doi.org/10.3390/ijms15057639
5 
%X Magnesium based implants could revolutionize applications where orthopedic implants such as nails, screws or bone plates are used because they are load bearing and degrade over time. This prevents a second surgery to remove conventional implants. To improve the biocompatibility we studied here if and for how long a pre-incubation of the material under cell culture conditions is favorable for cell attachment and proliferation. For two materials, Mg and Mg10Gd1Nd, we could show that 6 h pre-incubation are already enough to form a natural protective layer suitable for cell culture.