@misc{tian_hyaluronic_acidcoated_2018, 
author={Tian, Z.,Liu, J.,Li, N.,Haramus, V.M.,Zou, A.},
title={Hyaluronic acid-coated liposome for active targeting on CD44 expressing tumors},
year={2018},
howpublished = {journal article},
doi = {https://doi.org/10.1007/s11051-018-4324-1},
abstract = {Liposome coated with hyaluronic acid (HA) was fabricated for targeted delivery of Doxorubicin hydrochloride (DOX) to CD44 expressing tumors. DOX was incorporated into liposome (DOX-L) via a transmembrane pH-gradient method, which contributed to high encapsulation efficiency (97%) and drug loading (19%). HA was modified on the surface of DOX-L by simple vortex (HA-DOX-L). The average diameter of optimized DOX-L and H-DOX-L was 109.7 ± 3.1 and 117.2 ± 5.0 nm, respectively, with good uniformity and stability during 6-month storage. SAXS and TEM evidenced the corona of HA on the surface of DOX-L, which convinced the prolonged circulation of DOX. The apoptosis study demonstrated the improved efficacy of HA-DOX-L with the human colon cancer cell line HCT-116 cells in comparison to the conventional reservoirs. This improved efficacy of HA-DOX-L with HCT-116 cells should be related with the interaction between HA and CD44 receptor of HCT-116 cells.},
note = {Online available at: \url{https://doi.org/10.1007/s11051-018-4324-1} (DOI). Tian, Z.; Liu, J.; Li, N.; Haramus, V.; Zou, A.: Hyaluronic acid-coated liposome for active targeting on CD44 expressing tumors. Journal of Nanoparticle Research. 2018. vol. 20, 235. DOI: 10.1007/s11051-018-4324-1}}