@misc{peng_hexylmodified_morpholine25dionebased_2016, 
author={Peng, X.,Behl, M.,Zhang, P.,Mazurek-Budzynska, M.,Razzaq, M.Y.,Lendlein, A.},
title={Hexyl-modified morpholine-2,5-dione-based oligodepsipeptides with relatively low glass transition temperature},
year={2016},
howpublished = {journal article},
doi = {https://doi.org/10.1016/j.polymer.2016.10.033},
abstract = {Oligodepsipeptides (oDPs), alternating copolymers of an α-amino acid and an α-hydroxy acid, are typically created by ring-opening polymerization (ROP) of morpholine-2,5-dione derivatives (MDs). In general, oDPs exhibit relatively high glass transition temperatures (Tgs) caused by the strong intermolecular H-bonding between amide and ester bonds. So far, it was not reported that variation at α-amino acid moieties in MDs monomers lead to lower Tg. Here we explored whether the thermal properties of the oDPs can be adjusted by introducing a hexyl side chain in the α-hydroxy acid part of the MDs. By synthesizing a MD with an atactic pendant hexyl group at position 3, the influence of a modification at position 6 compared to a modification at position 3 towards ROP was investigated. In both cases the atactic bulky side groups hindered the H-bonding between chain segments resulting in a significant reduction of the Tgs to a temperature around human body temperature (32 and 36 °C) in contrast to ROP of a MD providing a methyl group at position 3 and a Tg ≈ 65 °C. Such oDPs could be interesting candidate materials for biomedical applications such as degradable implants.},
note = {Online available at: \url{https://doi.org/10.1016/j.polymer.2016.10.033} (DOI). Peng, X.; Behl, M.; Zhang, P.; Mazurek-Budzynska, M.; Razzaq, M.; Lendlein, A.: Hexyl-modified morpholine-2,5-dione-based oligodepsipeptides with relatively low glass transition temperature. Polymer. 2016. vol. 105, 318-326. DOI: 10.1016/j.polymer.2016.10.033}}