@misc{lv_biodegradable_depsipeptidepdopegbased_2014, author={Lv, J.,Zhang, L.,Khan, M.,Ren, X.,Guo, J.,Feng, Y.}, title={Biodegradable depsipeptide–PDO–PEG-based block copolymer micelles as nanocarriers for controlled release of doxorubicin}, year={2014}, howpublished = {journal article}, doi = {https://doi.org/10.1016/j.reactfunctpolym.2014.06.005}, abstract = {Nowadays, biodegradable amphiphilic block copolymers with stable performance and adjustable structure have attracted the interests of researchers in the field of drug delivery. In this work, the triblock copolymer, P(SBMD-co-PDO)-b-PEG-b-P(SBMD-co-PDO), was successfully synthesized by ring-opening polymerization of 3(S)-sec-butyl-morpholine-2,5-dione (SBMD) and p-dioxanone (PDO) with poly(ethylene glycol) (PEG) as the initiator. In phosphate buffered solution (PBS), these copolymers could self-assemble into nano-sized micelles that have a hydrophobic P(SBMD-co-PDO) core surrounded by a hydrophilic PEG shell. Because of the strong hydrogen bonding and hydrophobic interactions, doxorubicin (DOX) was loaded into the micelles with high loading capacity (LC, up to 28.4%) and encapsulation efficiency (EE, up to 62.5%).}, note = {Online available at: \url{https://doi.org/10.1016/j.reactfunctpolym.2014.06.005} (DOI). Lv, J.; Zhang, L.; Khan, M.; Ren, X.; Guo, J.; Feng, Y.: Biodegradable depsipeptide–PDO–PEG-based block copolymer micelles as nanocarriers for controlled release of doxorubicin. Reactive and Functional Polymers. 2014. vol. 82, 89-97. DOI: 10.1016/j.reactfunctpolym.2014.06.005}}