@misc{kulkarni_selective_enzymatic_2008, 
author={Kulkarni, A.,Reiche, J.,Hartmann, J.,Kratz, K.,Lendlein, A.},
title={Selective enzymatic degradation of poly (Epsilon-caprolactone) containing multiblock copolymers},
year={2008},
howpublished = {journal article},
doi = {https://doi.org/10.1016/j.ejpb.2007.05.021},
abstract = {The hydrolytic and Pseudomonas lipase catalysed enzymatic degradation was studied for PDC multiblock copolymers consisting of poly(e-caprolactone) (PCL) segments and poly(p-dioxanone) (PPDO) segments with variable composition. The enzymatic degradation of these multiblock copolymers is significantly accelerated by Pseudomonas lipase in contrast to the hydrolytic degradation where the deg-radation behaviour is determined by the PPDO segments. Degradation time intervals up to 200 h are selected, where the PPDO segments remain stable and do not contribute to the degradation process. A linear correlation between weight loss and increasing PCL content of the multiblock copolymers was found. X-ray diffraction data confirm that both crystalline and amorphous PCL are attacked by the enzymes. SEM cross-section images reveal that Pseudomonas lipase penetrates into the PDC polymers. The present study impressively demonstrates that selective enzymatic degradation of PCL containing multifunctional polymers is a beneficial tool for controlling their degradation properties.},
note = {Online available at: \url{https://doi.org/10.1016/j.ejpb.2007.05.021} (DOI). Kulkarni, A.; Reiche, J.; Hartmann, J.; Kratz, K.; Lendlein, A.: Selective enzymatic degradation of poly (Epsilon-caprolactone) containing multiblock copolymers. European Journal of Pharmaceutics and Biopharmaceutics. 2008. vol. 68, no. 1, 46-56. DOI: 10.1016/j.ejpb.2007.05.021}}